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Potential link found between Merck antiviral and mutated COVID strains

Published Sat, 22 Feb 2025 04:16:48 GMT

(The Hill) - A new study published Monday links COVID-19 antiviral created by Merck and new mutations of the virus that have been sequenced around the world.Molnupiravir, known commercially as Lagevrio, is one of two COVID-19 antivirals authorized for treating coronavirus infections along with Paxlovid from Pfizer. The drug works by inducing mutations in the virus's cells as it replicates, resulting in random mutations that are harmful to the virus and cuts down on its viral load.Researchers from the U.K. and South African delved into the question of where some mutated variants may have occurred, given that some have been found with seemingly random mutations, and whether molnupiravir may have contributed to the rise of some strains.In the study published in the Nature science journal, researchers looked at available data from patients who were treated with molnupiravir and those who were not. Their findings confirmed the drug's ability to cause high rates of mutations in the virus,...

Albany's Making Strides Against Breast Cancer walk on October 15

Published Sat, 22 Feb 2025 04:16:48 GMT

ALBANY, N.Y. (NEWS10) -- The 28th annual Capital Region Making Strides Against Breast Cancer walk will take place on October 15 in Albany's Washington Park Parade Grounds starting at 10 a.m. The walk is not only meant to support the fight against breast cancer, but to create a community for survivors, caregivers, and families affected. Get the latest news, weather, sports and entertainment delivered right to your inbox! Making Strides Against Breast Cancer walks are three to five miles and have emerged as one of the nation's biggest and most impactful breast cancer movements.According to the American Cancer Society, 18,780 women in New York are expected to be diagnosed with breast cancer, with over 4 million survivors in the U.S. today who are undergoing and have completed treatment. Due to earlier detection, the death rate from breast cancer has dropped by 42% from 1989 to 2019. Except for skin cancers, it is the most common cancer in women in the United States.

Suspects charged in homicide investigation

Published Sat, 22 Feb 2025 04:16:48 GMT

ST. LOUIS - Police have charged two people for a homicide that happened last Friday.21-year-old Joshua Conley and a 16-year-old juvenile were arrested Sunday after a short chase in the Marine Villa neighborhood. The police suspected them of a shooting that happened at the now-closed South City Hospital.  Little boy at the center of pizza coupon scam in Illinois Conley has been charged with first-degree murder and armed criminal action. He remains jailed without bond.

Absentee voting begins in today in St. Louis County for special Nov. 7 election

Published Sat, 22 Feb 2025 04:16:48 GMT

ST. LOUIS - Absentee voting for the November special election is open Tuesday in several areas.Only registered voters in several districts can vote in the special election. That includes the cities of Ladue, Manchester and St. John, the village of Riverview, and the Rockwood R6 School District. Cloned voice, fake bondsman target St. Louis woman They can request an absentee ballot starting Tuesday and must have mailed it in by October 25. The special election is November 7.

Everything you need to know to hike the Maroon Bells Four Pass Loop

Published Sat, 22 Feb 2025 04:16:48 GMT

One of the best moments on any hike is when you turn the corner or take that last step before the view takes your breath away. On this loop, you’ll experience that moment over and over and over again.“There’s not a single bad view on this loop,” my dad, David Fries, said multiple times as we backpacked the Maroon Bells Four Pass Loop.You’ll see wildlife and pass waterfalls, alpine lakes and rivers while hiking over four summits above 12,000 feet that overlook colorful valleys with blooming wildflowers and those iconic red mountain peaks. If you’re a backpacker, this one must go on your bucket list.A map of the Maroon Bells-Snowmass Wilderness overnight permit zones. (US Forest Service)This guide will help you plan and complete an epic Colorado backpacking trip.PLANNING YOUR TRIPPermitsTo camp overnight in the Maroon Bells-Snowmass Wilderness, permits are required year-round through recreation.gov. The best time to visit is between July and Septemb...

Thousands in cash and jewelry taken in Canoga Park home-invasion robbery

Published Sat, 22 Feb 2025 04:16:48 GMT

Police are searching for five home-invasion robbery suspects who stole cash and jewelry from victims at a Canoga Park apartment complex Tuesday morning.The incident was reported around 1:30 a.m. in the 21000 block of Vanowen Street.Police are searching for five robbery suspects in Canoga Park on Sept. 26, 2023. (KTLA)The five suspects, armed with a gun and a large kitchen knife, forced their way into an apartment unit and robbed the victims, a Los Angeles Police Department spokesperson confirmed. Investigators believe the suspects got away with about $5,000 in cash and jewelry. Eviction notices piling up in Los Angeles Police are searching for suspects who were wearing surgical masks and dressed in all black.No injuries were reported.

What Are The Possible Side Effects of Taking Delta-8 THC?

Published Sat, 22 Feb 2025 04:16:48 GMT

Despite its recent history, delta-8 THC has gained a reputation as the “diet” version of standard delta-9 THC. Many anecdotal testimonies and surveys suggest that delta-8 extracts don’t have the same intensity as delta-9-rich marijuana strains. Sure, delta-8 will give you a “high” sensation, but it doesn’t seem to be as “in your face” as comparable delta-9 items.However, just because delta-8 seems to be “weaker” than delta-9 THC doesn’t mean it’s as tame as CBD oil. Delta-8 THC will land on the brain’s CB1 receptors, which means there’s a greater potential for side effects. Customers new to THC must understand that delta-8 could provoke many “weird” adverse reactions. Although some of these symptoms may feel scary, they are commonly reported by people who are extra sensitive to THC.Common Delta-8 Reactions To Be Prepared For1.   ParanoiaParanoia and panic attacks are the most severe side effects most people report when taking delta-8 THC. A few trials suggest our genetics play a rol...

iCandy and Flo Milli Get Big Mad

Published Sat, 22 Feb 2025 04:16:48 GMT

iCandy and Flo Milli Get Big Mad: Rising hip-hop artist iCandy has followed up her “Keep Dat” single with “Big Mad,” a collaboration with Flo Milli.“’Keep Dat’ became a TikTok staple hitting #1 on 6 Spotify charts and #1 on TikTok viral,” reads a press release. “iCandy recruited the rap games current top females for the remix, “Keep Dat” part 2, featuring GloRilla, Kali and Big Boss Vette, listen HERE.”“iCandy’s name began flooding the national consciousness in late 2022 when the Pompano Beach Florida native first released ‘Keep Dat,’ the playful, confident, and effortlessly bold track which now serves up soundtracks for girls’ night and permanently altered Candy’s trajectory,” it continues. “Candy’s magnetic personality and strong advocation for women’s empowerment, keeps a close relationship with her growing fans online. She made her debut at Rolling Loud Miami in July popping out with GloRilla &am...

Warriors: Digging deeper into Dunleavy and Kerr comments ahead of training camp

Published Sat, 22 Feb 2025 04:16:48 GMT

SAN FRANCISCO — Steve Kerr and Mike Dunleavy Jr. spoke with reporters a week before Warriors training camp is set to open on Oct. 2. The Warriors are intent on proving the dynasty has plenty left in the tank.Here are some takeaways from their comments.Open roster spotsAround 40-to-50 players came through Chase Center for workouts throughout the summer, Dunleavy said. Some of those names include Dwight Howard, Juan Toscano-Anderson and Kent Bazemore. The Warriors will have some competition at training camp for two open roster spots and a two-way spot available.They may not use both roster spots and there is no urgent positional need on the roster — the team aims to add the best player available.“I think maybe we have already pursued and committed to that,” Dunleavy said. “Nice thing is I think we have good versatility and optionality throughout the roster, so nothing that we absolutely have to do right now. We are bringing in a mix of different players t...

Pedestrian killed in East San Jose traffic collision

Published Sat, 22 Feb 2025 04:16:48 GMT

SAN JOSE — A pedestrian died early Tuesday morning after he was struck by a vehicle in East San Jose, according to authorities.Police said officers were alerted to a collision involving a vehicle and a pedestrian around 3:23 a.m. Tuesday on the 40 block of South Jackson Avenue in East San Jose, about one block south of Alum Rock Avenue.The man was pronounced dead at the scene, police said. The driver remained on the scene and cooperated with the investigation.Related ArticlesCrashes and Disasters | Driver hits, kills pedestrian in Willow Glen Crashes and Disasters | Motorist, horse killed in California collision Crashes and Disasters | Hit-and-run in Oakland kills two East Bay residents in their 60s Crashes and Disasters | Man hit and killed by driver in West San Jose Crashes and Disasters | Family sues Google alleging its Maps app led father to drive off collapsed bridge to his death No additional detai...